A 42 year old man who has industrial exposure to benzene


Question Number 0827
Question:
A 42 year old man who has industrial exposure to benzene, complains of fatigue, abdominal fullness and night sweats. Finally, because his wife insists, he sees his doctor. On physical examination, he is found to have a low grade fever and dramatic splenomegaly. His doctor comments that he has never seen such splenomegaly. Laboratory tests are done, including a CBC with differential. His white blood count is 150,000/cu mm. His blood smear shows mature granulocytes, a few immature granulocytes and basophilia. No Auer rods are visualized. He is positive for Philadelphia chromosome. Which of the following is most likely?
a) acute lymphoblastic leukemia
b) acute myelogenous leukemia
c) chronic lymphoblastic leukemia
d) chronic myelogenous leukemia
e) hairy cell leukemia


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