Answer :USMLE step 2 Mcq 181:16 year old girl is brought by her mother to her physician




Correct Answer: D

The manifestations of congenital adrenal hyperplasia, because of excess androgens, may be similar to Cushing's syndrome. Congenital adrenal hyperplasia is generally diagnosed prior to puberty, and heterosexual precocious pseudopuberty is typical. However, if the defect is mild and changes to the external genitalia are minimal, masculinization may occur at the expected age of puberty. This attenuated or nonclassic form of 21-hydroxylase deficiency seems to occur in families with a strong family history of hirsutism. Affected girls generally have some defeminization with flattening of the breasts, severe hirsutism, relatively short stature, and obesity


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