MCQS 223-225:in a patient with cirrhosis of the liver , hepatocellular carcinoma is most likely to be associated with a raised

image 

Question:223
A patient presents with a red, indurated, non tender subcutaneous mass in the anterior cervical triangle. The overlying skin has a purplish discoloration. There are several draining sinuses present , sulfur granules are detected on microscopic examination

a) Actinomycosis
b) syphilis
c) Cat-Scratch Disease
d) Mycobacterium leprae
e) Mycobacterium tuberculosis
f) Leishmaniasis
g) Pyogenic granuloma
h) Eosinophilic granuloma
i) Hand-Schuller-Christian disease
j) Benign fibrous histiocytoma

.

 

Question:224
in a patient with cirrhosis of the liver , hepatocellular carcinoma is most likely to be associated with a raised

a) antigen CA-125
b) antigen CA15-3
c) prostatic specific antigen
d) serum HCG
e) serum AFP level
f) alkaline phosphatase
g) prostatic endothelin antagonists
h) hepatocyte growth factor
i) carcino-embryonic antigen (CEA)
j) interleukin-6

 

 

Question:225
the most common sex chromosomal aneuploidy in males is

a) XX karyotype
b) XXY karyotype
c) XO karyotype
d) XXX karyotype
e) XY karyotype
f) YO karyotype
g) XYY karyotype
h) Trisomy 13
i) Trisomy 18
j) Trisomy 21

 

Question:223
 
Correct Answer: A

Explanation:
Actinomycosis is an indolent suppurative infection caused by an anaerobic or microaerophilic organism. Infection follows after aspiration of the Actinomyces organism into the lung, or contact of the organism with damaged mucosa (i.e. poor dental hygiene, dental abscess). Pathologically, the agent grows in characteristic grains. The infectious process is walled off by the granulomatous inflammatory process with extensive fibrosis demonstrated on histological studies. Cervicofacial actinomycosis typically presents as a red, indurated, non tender subcutaneous mass in the anterior cervical triangle or submandibular region. The overlying skin may have a purplish discoloration. There may be several draining sinuses present (61% of patients). In addition, 57-89% of patients report fever, while other symptoms include weight loss, malaise, nausea, vomiting, and sweating. Demonstration of characteristic sulfur granules on microscopic examination provides the diagnosis with confirmation by culture. Treatment consists of oral penicillin or tetracycline for 2-4 months (mild cases) or 6 weeks of parenteral penicillin g (severe cases). Surgical debridement of necrotic tissue may be necessary to facilitate recovery.

 

Question:224
 
Correct Answer: E

Explanation:
Because patients with cirrhosis of the liver are at risk for developing HCC, serum levels of AFP have been used in this group to diagnose HCC. Elevations of serum AFP levels are seen in approximately 85% of patients who have HCC within a cirrhotic liver. In patients with cirrhosis without HCC, only 5% have elevated serum AFP levels

 

Question:225
Correct Answer: B

Explanation:
Klinefelter's syndrome occurs in approximately 1/500 to 1/1,000 newborn males. There is a 47XXY chromosome complement, representing the most common sex chromosomal aneuploidy in males


Labels:



>>>> Post your Answer Here ????



Design by Up2date.us